CD40 Signaling in Graves Disease Is Mediated Through Canonical and Noncanonical Thyroidal Nuclear Factor κB Activation

CD40, a tumor necrosis factor receptor, is a major immune-modulating susceptibility gene for Graves disease (GD) as well as for a variety of other autoimmune diseases. Its broad association with autoimmunity underscores its paramount role in the development of a normal adaptive immune response, prim...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Lee, Hanna J., Lombardi, Angela, Stefan, Mihaela, Li, Cheuk wun, Inabnet, William B., Owen, Randall P., Concepcion, Erlinda, Tomer, Yaron
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413074/
https://ncbi.nlm.nih.gov/pubmed/27929668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1609
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