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Genetic–epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunity
Graves disease (GD) is an autoimmune condition caused by interacting genetic and environmental factors. Genetic studies have mapped several single-nucleotide polymorphisms (SNPs) that are strongly associated with GD, but the mechanisms by which they trigger disease are unknown. We hypothesized that...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151767/ https://ncbi.nlm.nih.gov/pubmed/25122677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408821111 |
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