Does Dynorphin Play a Role in the Onset of Puberty in Female Sheep?

Puberty onset involves increased GnRH release due to decreased sensitivity to oestrogen (E)-negative feedback. Because GnRH neurones lack E receptor alpha, this pathway must contain interneurones. One likely candidate is KNDy neurones (kisspeptin, neurokinin B, dynorphin). Our overarching hypothesis...

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Detalhes bibliográficos
Publicado no:J Neuroendocrinol
Main Authors: Lopez, Justin A., Bedenbaugh, Michelle N., McCosh, Richard B., Weems, Peyton W., Meadows, Lanny J., Wisman, Brandon, Coolen, Lique M., Goodman, Robert L., Hileman, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412962/
https://ncbi.nlm.nih.gov/pubmed/28328155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jne.12445
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