Lataa...

Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations

Regulatory authorities require that the sample size of a confirmatory trial is calculated prior to the start of the trial. However, the sample size quite often depends on parameters that might not be known in advance of the study. Misspecification of these parameters can lead to under‐ or overestima...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biom J
Päätekijät: Kunz, Cornelia U., Stallard, Nigel, Parsons, Nicholas, Todd, Susan, Friede, Tim
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412911/
https://ncbi.nlm.nih.gov/pubmed/27886393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201500233
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!