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Activation of the hypoxia‐inducible factor pathway induced by prolyl hydroxylase domain 2 deficiency enhances the effect of running training in mice

AIMS: Hypoxic response mediated by hypoxia‐inducible factor (HIF) seems to contribute to the benefit of endurance training. To verify the direct contribution of HIF activation to running training without exposure to atmospheric hypoxia, we used prolyl hydroxylase domain 2 (PHD2) conditional knockout...

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Veröffentlicht in:Acta Physiol (Oxf)
Hauptverfasser: Nunomiya, A., Shin, J., Kitajima, Y., Dan, T., Miyata, T., Nagatomi, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412909/
https://ncbi.nlm.nih.gov/pubmed/27393382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12751
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