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Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2

Caspases are key enzymes responsible for mediating apoptotic cell death. Across species, caspase‐2 is the most conserved caspase and stands out due to unique features. Apart from cell death, caspase‐2 also regulates autophagy, genomic stability and ageing. Caspase‐2 requires dimerization for its act...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Imre, Gergely, Berthelet, Jean, Heering, Jan, Kehrloesser, Sebastian, Melzer, Inga Maria, Lee, Byung Il, Thiede, Bernd, Dötsch, Volker, Rajalingam, Krishnaraj
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412904/
https://ncbi.nlm.nih.gov/pubmed/28336776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643744
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