Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

Bacterial pathogens modulate host cell apoptosis to establish a successful infection. Pore-forming toxins (PFTs) secreted by pathogenic bacteria are major virulence factors and have been shown to induce various forms of cell death in infected cells. Here we demonstrate that the highly conserved casp...

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Detalhes bibliográficos
Main Authors: Imre, Gergely, Heering, Jan, Takeda, Armelle-Natsuo, Husmann, Matthias, Thiede, Bernd, zu Heringdorf, Dagmar Meyer, Green, Douglas R, van der Goot, F Gisou, Sinha, Bhanu, Dötsch, Volker, Rajalingam, Krishnaraj
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365430/
https://ncbi.nlm.nih.gov/pubmed/22531785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.93
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