The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death

The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ubiquitin ligase which catalyses the generation of linear ubiquitin linkages de novo. LUBAC is a crucial component of various immune receptor signalling pathways. Here, we show that LUBAC forms part of the TRAIL‐R‐associated co...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Lafont, Elodie, Kantari‐Mimoun, Chahrazade, Draber, Peter, De Miguel, Diego, Hartwig, Torsten, Reichert, Matthias, Kupka, Sebastian, Shimizu, Yutaka, Taraborrelli, Lucia, Spit, Maureen, Sprick, Martin R, Walczak, Henning
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412822/
https://ncbi.nlm.nih.gov/pubmed/28258062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695699
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