The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death

The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ubiquitin ligase which catalyses the generation of linear ubiquitin linkages de novo. LUBAC is a crucial component of various immune receptor signalling pathways. Here, we show that LUBAC forms part of the TRAIL‐R‐associated co...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Lafont, Elodie, Kantari‐Mimoun, Chahrazade, Draber, Peter, De Miguel, Diego, Hartwig, Torsten, Reichert, Matthias, Kupka, Sebastian, Shimizu, Yutaka, Taraborrelli, Lucia, Spit, Maureen, Sprick, Martin R, Walczak, Henning
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412822/
https://ncbi.nlm.nih.gov/pubmed/28258062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695699
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