Melatonin Ameliorates The Production of COX-2, iNOS, and The Formation of 8-OHdG in Non-Targeted Lung Tissue after Pelvic Irradiation

In this study, we evaluated the bystander effect of radiation on the regulation of cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and 8-hydroxydeoxyguanosine (8-OHdG) in lung tissues of Sprague-Dawley rats with and without pre-administration of melatonin. A 2×2 cm(2) area of the p...

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Veröffentlicht in:Cell J
Hauptverfasser: Fardid, Reza, Salajegheh, Ashkan, Mosleh-Shirazi, Mohammad Amin, Sharifzadeh, Sedigheh, Okhovat, Mohammad Ali, Najafi, Masoud, Rezaeyan, Abolhasan, Abaszadeh, Akbar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royan Institute 2017
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412791/
https://ncbi.nlm.nih.gov/pubmed/28670525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2016.3857
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