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The significance of the alteration of 8-OHdG in serous ovarian carcinoma

BACKGROUND: Oxidative damage and DNA repair dysfunction are associated with carcinogenesis. 8-OHdG is one of the major oxidative DNA adducts. Present work aims to investigate whether the expression of 8-OHdG and its key repair gene hOGG1 play distinctive role in two types of serous ovarian cancer. M...

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Détails bibliographiques
Auteurs principaux: Xu, Xia, Wang, Yan, Guo, Wenwen, Zhou, Yiqing, Lv, Chunmei, Chen, Xiaoxiang, Liu, Kaijiang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875897/
https://ncbi.nlm.nih.gov/pubmed/24165045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-6-74
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