8OHdG is not a biomarker for Huntington disease state or progression

OBJECTIVE: To evaluate plasma 8-hydroxy-deoxy-guanosine (8OHdG) levels as a potential biomarker of premanifest and early Huntington disease (HD). METHODS: Personnel from 2 independent laboratories quantified 8OHdG in blinded longitudinal plasma samples taken 24 months apart from 160 TRACK-HD partici...

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Detalhes bibliográficos
Main Authors: Borowsky, Beth, Warner, John, Leavitt, Blair R., Tabrizi, Sarah J., Roos, Raymund A.C., Durr, Alexandra, Becker, Chris, Sampaio, Cristina, Tobin, Allan J., Schulman, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716347/
https://ncbi.nlm.nih.gov/pubmed/23616162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318293e1a1
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