A Computational Cognitive Biomarker for Early-Stage Huntington’s Disease

Huntington’s disease (HD) is genetically determined but with variability in symptom onset, leading to uncertainty as to when pharmacological intervention should be initiated. Here we take a computational approach based on neurocognitive phenotyping, computational modeling, and classification, in an...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Wiecki, Thomas V., Antoniades, Chrystalina A., Stevenson, Alexander, Kennard, Christopher, Borowsky, Beth, Owen, Gail, Leavitt, Blair, Roos, Raymund, Durr, Alexandra, Tabrizi, Sarah J., Frank, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752511/
https://ncbi.nlm.nih.gov/pubmed/26872129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148409
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