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8OHdG as a marker for Huntington disease progression

Leukocyte 8-hydroxydeoxyguanosine (8OHdG) is an indicator of oxidative stress, impaired metabolism, and mitochondrial dysfunction, features that have been implicated in Huntington disease (HD). Increased levels of 8OHdG have been reported in the caudate, parietal cortex, and peripherally in the seru...

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Autori principali: Long, Jeffrey D., Matson, Wayne R., Juhl, Andrew R., Leavitt, Blair R., Paulsen, Jane S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784019/
https://ncbi.nlm.nih.gov/pubmed/22414782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.02.012
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