Antibodies inhibit transmission and aggregation of C9orf72 poly‐GA dipeptide repeat proteins

Cell‐to‐cell transmission of protein aggregates is an emerging theme in neurodegenerative disease. Here, we analyze the dipeptide repeat (DPR) proteins that form neuronal inclusions in patients with hexanucleotide repeat expansion C9orf72, the most common known cause of amyotrophic lateral sclerosis...

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Библиографические подробности
Опубликовано в: :EMBO Mol Med
Главные авторы: Zhou, Qihui, Lehmer, Carina, Michaelsen, Meike, Mori, Kohji, Alterauge, Dominik, Baumjohann, Dirk, Schludi, Martin H, Greiling, Johanna, Farny, Daniel, Flatley, Andrew, Feederle, Regina, May, Stephanie, Schreiber, Franziska, Arzberger, Thomas, Kuhm, Christoph, Klopstock, Thomas, Hermann, Andreas, Haass, Christian, Edbauer, Dieter
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
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Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412769/
https://ncbi.nlm.nih.gov/pubmed/28351931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607054
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