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Structural and functional basis of the developmental regulation of human coagulation factor IX gene: factor IX Leyden.

Hemophilia B Leyden is characterized by unusual developmental regulation of factor IX synthesis in affected individuals. One family affected with the hemophilia B Leyden phenotype was found to have a specific single-base mutation (G----A) at nucleotide -6 of the factor IX gene. The mutation site was...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hirosawa, S, Fahner, J B, Salier, J P, Wu, C T, Lovrien, E W, Kurachi, K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2352926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4421
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