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Structural and functional basis of the developmental regulation of human coagulation factor IX gene: factor IX Leyden.

Hemophilia B Leyden is characterized by unusual developmental regulation of factor IX synthesis in affected individuals. One family affected with the hemophilia B Leyden phenotype was found to have a specific single-base mutation (G----A) at nucleotide -6 of the factor IX gene. The mutation site was...

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Bibliografiska uppgifter
Huvudupphovsmän: Hirosawa, S, Fahner, J B, Salier, J P, Wu, C T, Lovrien, E W, Kurachi, K
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC54126/
https://ncbi.nlm.nih.gov/pubmed/2352926
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