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Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice

Colorectal cancer is a common cancer worldwide. Carbonic anhydrase (CA) catalyzes the reversible conversion of carbon dioxide to bicarbonate ion and a proton, and its inhibitor is reported to reduce cancer cell proliferation and induce apoptosis. Therefore, we asked whether acetazolamide, a CA inhib...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Noma, Nobuharu, Fujii, Gen, Miyamoto, Shingo, Komiya, Masami, Nakanishi, Ruri, Shimura, Misato, Tanuma, Sei-ichi, Mutoh, Michihiro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412435/
https://ncbi.nlm.nih.gov/pubmed/28420165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040851
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