Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

Ghrelin, an orexigenic hormone released primarily from the gut, signals the hypothalamus to stimulate growth hormone release, enhance appetite and promote weight gain. The ghrelin receptor, aka Growth Hormone Secretagogue Receptor (GHS-R), is highly expressed in the brain, with highest expression in...

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Pubblicato in:Int J Mol Sci
Autori principali: Wu, Chia-Shan, Bongmba, Odelia Y. N., Yue, Jing, Lee, Jong Han, Lin, Ligen, Saito, Kenji, Pradhan, Geetali, Li, De-Pei, Pan, Hui-Lin, Xu, Allison, Guo, Shaodong, Xu, Yong, Sun, Yuxiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412416/
https://ncbi.nlm.nih.gov/pubmed/28420089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040832
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