Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

Ghrelin, an orexigenic hormone released primarily from the gut, signals the hypothalamus to stimulate growth hormone release, enhance appetite and promote weight gain. The ghrelin receptor, aka Growth Hormone Secretagogue Receptor (GHS-R), is highly expressed in the brain, with highest expression in...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wu, Chia-Shan, Bongmba, Odelia Y. N., Yue, Jing, Lee, Jong Han, Lin, Ligen, Saito, Kenji, Pradhan, Geetali, Li, De-Pei, Pan, Hui-Lin, Xu, Allison, Guo, Shaodong, Xu, Yong, Sun, Yuxiang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412416/
https://ncbi.nlm.nih.gov/pubmed/28420089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040832
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