Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

Ghrelin, an orexigenic hormone released primarily from the gut, signals the hypothalamus to stimulate growth hormone release, enhance appetite and promote weight gain. The ghrelin receptor, aka Growth Hormone Secretagogue Receptor (GHS-R), is highly expressed in the brain, with highest expression in...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Wu, Chia-Shan, Bongmba, Odelia Y. N., Yue, Jing, Lee, Jong Han, Lin, Ligen, Saito, Kenji, Pradhan, Geetali, Li, De-Pei, Pan, Hui-Lin, Xu, Allison, Guo, Shaodong, Xu, Yong, Sun, Yuxiang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412416/
https://ncbi.nlm.nih.gov/pubmed/28420089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040832
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