Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2

[Image: see text] 17β-Hydroxysteroid dehydrogenase type 2 (17β-HSD2) converts the active steroid hormones estradiol, testosterone, and 5α-dihydrotestosterone into their weakly active forms estrone, Δ(4)-androstene-3,17-dione, and 5α-androstane-3,17-dione, respectively, thereby regulating cell- and t...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Vuorinen, Anna, Engeli, Roger T., Leugger, Susanne, Bachmann, Fabio, Akram, Muhammad, Atanasov, Atanas G., Waltenberger, Birgit, Temml, Veronika, Stuppner, Hermann, Krenn, Liselotte, Ateba, Sylvin B., Njamen, Dieudonné, Davis, Rohan A., Odermatt, Alex, Schuster, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411959/
https://ncbi.nlm.nih.gov/pubmed/28319389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.6b00950
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