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HySA: a Hybrid Structural variant Assembly approach using next-generation and single-molecule sequencing technologies

Achieving complete, accurate, and cost-effective assembly of human genomes is of great importance for realizing the promise of precision medicine. The abundance of repeats and genetic variations in human genomes and the limitations of existing sequencing technologies call for the development of nove...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Fan, Xian, Chaisson, Mark, Nakhleh, Luay, Chen, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411774/
https://ncbi.nlm.nih.gov/pubmed/28104618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.214767.116
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