Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction

Among the five serine incorporator (SERINC) family members, SERINC5 (Ser5) was reported to strongly inhibit HIV-1 replication, which is counteracted by Nef. Ser5 produces 5 alternatively spliced isoforms: Ser5-001 has 10 putative transmembrane domains, whereas Ser5-004, -005, -008a, and -008b do not...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Xianfeng, Zhou, Tao, Yang, Jie, Lin, Yumei, Shi, Jing, Zhang, Xihe, Frabutt, Dylan A., Zeng, Xiangwei, Li, Sunan, Venta, Patrick J., Zheng, Yong-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411613/
https://ncbi.nlm.nih.gov/pubmed/28275190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00137-17
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