Pathways of Prion Spread during Early Chronic Wasting Disease in Deer

Among prion infections, two scenarios of prion spread are generally observed: (i) early lymphoid tissue replication or (ii) direct neuroinvasion without substantial antecedent lymphoid amplification. In nature, cervids are infected with chronic wasting disease (CWD) prions by oral and nasal mucosal...

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Bibliographic Details
Published in:J Virol
Main Authors: Hoover, Clare E., Davenport, Kristen A., Henderson, Davin M., Denkers, Nathaniel D., Mathiason, Candace K., Soto, Claudio, Zabel, Mark D., Hoover, Edward A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Prions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411598/
https://ncbi.nlm.nih.gov/pubmed/28250130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00077-17
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