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Assessment of Chronic Wasting Disease Prion Shedding in Deer Saliva with Occupancy Modeling

The detection of prions is difficult due to the peculiarity of the pathogen, which is a misfolded form of a normal protein. The specificity and sensitivity of detection methods are imperfect in complex samples, including in excreta. Here, we combined optimized prion amplification procedures with a s...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Davenport, Kristen A., Mosher, Brittany A., Brost, Brian M., Henderson, Davin M., Denkers, Nathaniel D., Nalls, Amy V., McNulty, Erin, Mathiason, Candace K., Hoover, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744203/
https://ncbi.nlm.nih.gov/pubmed/29118163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01243-17
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