Longitudinal Detection of Prion Shedding in Saliva and Urine by Chronic Wasting Disease-Infected Deer by Real-Time Quaking-Induced Conversion

Chronic wasting disease (CWD) is an emergent, rapidly spreading prion disease of cervids. Shedding of infectious prions in saliva and urine is thought to be an important factor in CWD transmission. To help to elucidate this issue, we applied an in vitro amplification assay to determine the onset, du...

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Bibliographic Details
Published in:J Virol
Main Authors: Henderson, Davin M., Denkers, Nathaniel D., Hoover, Clare E., Garbino, Nina, Mathiason, Candace K., Hoover, Edward A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Prions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542351/
https://ncbi.nlm.nih.gov/pubmed/26136567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01118-15
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