Modulation of Hepatitis C Virus-Specific CD8 Effector T-Cell Function with Antiviral Effect in Infectious Hepatitis C Virus Coculture Model

The antiviral effects of hepatitis C virus (HCV)-specific CD8 T cells have been shown in an HCV replicon system but not in an authentic infectious HCV cell culture (HCVcc) system. Here, we developed tools to examine the antigenicity of HCV-infected HLA-A2-positive Huh7.5 hepatoma cells (Huh7.5A2 cel...

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Veröffentlicht in:J Virol
Hauptverfasser: Ojiro, Keisuke, Qu, Xiaowang, Cho, Hyosun, Park, Jang-June, Vuidepot, Annelise, Lissin, Nikolai, Molloy, Peter E., Bennett, Alan, Jakobsen, Bent K., Kaplan, David E., Riley, James L., Chang, Kyong-Mi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411593/
https://ncbi.nlm.nih.gov/pubmed/28275182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02129-16
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