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A Mitochondrial Autonomously Replicating Sequence from Pichia pastoris for Uniform High Level Recombinant Protein Production

Pichia pastoris is a non-conventional methylotrophic yeast that is widely used for recombinant protein production, typically by stably integrating the target gene into the genome as part of an expression cassette. However, the comparatively high clonal variability associated with this approach usual...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Schwarzhans, Jan-Philipp, Luttermann, Tobias, Wibberg, Daniel, Winkler, Anika, Hübner, Wolfgang, Huser, Thomas, Kalinowski, Jörn, Friehs, Karl
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411459/
https://ncbi.nlm.nih.gov/pubmed/28512458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00780
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