A Mitochondrial Autonomously Replicating Sequence from Pichia pastoris for Uniform High Level Recombinant Protein Production

Pichia pastoris is a non-conventional methylotrophic yeast that is widely used for recombinant protein production, typically by stably integrating the target gene into the genome as part of an expression cassette. However, the comparatively high clonal variability associated with this approach usual...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Schwarzhans, Jan-Philipp, Luttermann, Tobias, Wibberg, Daniel, Winkler, Anika, Hübner, Wolfgang, Huser, Thomas, Kalinowski, Jörn, Friehs, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411459/
https://ncbi.nlm.nih.gov/pubmed/28512458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00780
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