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A comparison of modular PEG incorporation strategies for stabilization of peptide-siRNA nanocomplexes

Nanoparticulate systems have shown great promise in overcoming the considerable trafficking barriers associated with systemic nucleic acid delivery, which must be addressed in order to unlock the full potential of technologies such as RNAi and gene editing in vivo. In addition to mediating the cytop...

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Библиографические подробности
Опубликовано в: :Bioconjug Chem
Главные авторы: Lo, Justin H., Kwon, Ester J., Zhang, Angela Q., Singhal, Preeti, Bhatia, Sangeeta N.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410868/
https://ncbi.nlm.nih.gov/pubmed/27583545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00304
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