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A comparison of modular PEG incorporation strategies for stabilization of peptide-siRNA nanocomplexes

Nanoparticulate systems have shown great promise in overcoming the considerable trafficking barriers associated with systemic nucleic acid delivery, which must be addressed in order to unlock the full potential of technologies such as RNAi and gene editing in vivo. In addition to mediating the cytop...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Lo, Justin H., Kwon, Ester J., Zhang, Angela Q., Singhal, Preeti, Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410868/
https://ncbi.nlm.nih.gov/pubmed/27583545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00304
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