iRGD-guided tumor penetrating nanocomplexes for therapeutic siRNA delivery to pancreatic cancer

Pancreatic cancer is one of the leading causes of cancer death, with 5-year survival of 8.5%. The lack of significant progress in improving therapy reflects our inability to overcome the desmoplastic stromal barrier in pancreatic ductal adenocarcinoma (PDAC) as well as a paucity of new approaches ta...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Lo, Justin H., Hao, Liangliang, Muzumdar, Mandar D., Raghavan, Srivatsan, Kwon, Ester J., Pulver, Emilia M., Hsu, Felicia, Aguirre, Andrew J., Wolpin, Brian M., Fuchs, Charles S., Hahn, William C., Jacks, Tyler, Bhatia, Sangeeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298224/
https://ncbi.nlm.nih.gov/pubmed/30097486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-1090
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