Design of a Multicomponent Peptide-Woven Nanocomplex for Delivery of siRNA

We developed and tested a multicomponent peptide-woven siRNA nanocomplex (PwSN) comprising different peptides designed for efficient cellular targeting, endosomal escape, and release of siRNA. To enhance tumor-specific cellular uptake, we connected an interleukin-4 receptor-targeting peptide (I4R) t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jun, Eunsung, Kim, Soyoun, Kim, Jong-Ho, Cha, Kiweon, So, In-Seop, Son, Hye-Nam, Lee, Byung-Heon, Kim, Kwangmeyung, Kwon, Ick Chan, Kim, Sang Yoon, Kim, In-San
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338040/
https://ncbi.nlm.nih.gov/pubmed/25705892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118310
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