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In situ structural studies of tripeptidyl peptidase II (TPPII) reveal spatial association with proteasomes

Tripeptidyl peptidase II (TPPII) is a eukaryotic protease acting downstream of the 26S proteasome; it removes tripeptides from the degradation products released by the proteasome. Structural studies in vitro have revealed the basic architecture of TPPII, a two-stranded linear polymer that assembles...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fukuda, Yoshiyuki, Beck, Florian, Plitzko, Jürgen M., Baumeister, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410853/
https://ncbi.nlm.nih.gov/pubmed/28396430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701367114
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