The B(12)-Radical SAM Enzyme PoyC Catalyzes Valine C(β)-Methylation during Polytheonamide Biosynthesis

[Image: see text] Genomic and metagenomic investigations have recently led to the delineation of a novel class of natural products called ribosomally synthesized and post-translationally modified peptides (RiPPs). RiPPs are ubiquitous among living organisms and include pharmaceutically relevant comp...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Parent, Aubérie, Guillot, Alain, Benjdia, Alhosna, Chartier, Gwladys, Leprince, Jérôme, Berteau, Olivier
Format: Artigo
Language:Inglês
Published: American Chemical Society 2016
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410653/
https://ncbi.nlm.nih.gov/pubmed/27934015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b06697
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