The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells

PUMA is a member of the “BH3-only” branch of the BCL-2 family. Our previous study suggests a therapeutic potential of PUMA in treating ovarian cancer, however, the action mechanism of PUMA remains elusive. In this work, we found that in PUMA adenovirus-infected A2780s ovarian cancer cells, exogenous...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Jun, Zhao, Xinyu, Tang, Mei, Li, Lei, Lei, Yi, Cheng, Ping, Guo, Wenhao, Zheng, Yu, Wang, Wei, Luo, Na, Peng, Yong, Tong, Aiping, Wei, Yuquan, Nie, Chunlai, Yuan, Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410321/
https://ncbi.nlm.nih.gov/pubmed/28423586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15626
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