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The role of ROS and subsequent DNA-damage response in PUMA-induced apoptosis of ovarian cancer cells
PUMA is a member of the “BH3-only” branch of the BCL-2 family. Our previous study suggests a therapeutic potential of PUMA in treating ovarian cancer, however, the action mechanism of PUMA remains elusive. In this work, we found that in PUMA adenovirus-infected A2780s ovarian cancer cells, exogenous...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410321/ https://ncbi.nlm.nih.gov/pubmed/28423586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15626 |
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