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CD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis
CD47 is a transmembrane protein that functions as a receptor for thrombospondin-1 (TSP1) and a ligand for inhibitory receptor signal-regulatory protein-α (SIRPα). Blocking the interaction between CD47 on tumor cells and SIRPα on macrophages has been shown to induce antitumor responses. Here we inves...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410232/ https://ncbi.nlm.nih.gov/pubmed/27283989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9899 |
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