GRK6 deficiency promotes angiogenesis, tumor progression and metastasis

G protein coupled receptor kinases (GRKs) phosphorylate the activated form of G protein coupled receptors (GPCRs) leading to receptor desensitization and down-regulation. We have recently shown that the chemokine receptor, CXCR2, couples to GRK6 to regulate cellular responses including chemotaxis, a...

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Autors principals: Raghuwanshi, Sandeep K., Smith, Nikia, Rivers, Elizabeth, J., Thomas, Ariel J., Sutton, Natalie, Hu, Yuhui, Mukhopadhyay, Somnath, Chen, Xiaoxin L., Leung, TinChung, Richardson, Ricardo M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646980/
https://ncbi.nlm.nih.gov/pubmed/23589623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202058
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