Thrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells

CD47 signaling in endothelial cells has been shown to suppress angiogenesis, but little is known about the link between CD47 and endothelial senescence. Herein, we demonstrate that the thrombospondin-1 (TSP1)-CD47 signaling pathway is a major mechanism for driving endothelial cell senescence. CD47 d...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Gao, Qi, Chen, Kexin, Gao, Lu, Zheng, Yang, Yang, Yong-Guang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059850/
https://ncbi.nlm.nih.gov/pubmed/27607583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.155
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items