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The CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cells

BACKGROUND & AIMS: A fenestrated phenotype is characteristic of liver sinusoidal endothelial cells (LSECs), but liver sinusoids become defenestrated during fibrosis and other liver diseases. Thrombospondin-1 (TSP1) is a matrix glycoprotein with pro-fibrotic effects, and the CD47-binding fragment...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Liver Int
Prif Awduron: Venkatraman, Lakshmi, Tucker-Kellogg, Lisa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285809/
https://ncbi.nlm.nih.gov/pubmed/23799952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12231
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