Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration

Aldosterone, with pro-oxidation and pro-autophagy capabilities, plays a key role in liver fibrosis. However, the mechanisms underlying aldosterone-promoted liver sinusoidal endothelial cells (LSECs) defenestration remain unknown. Caveolin 1 (Cav1) displays close links with autophagy and fenestration...

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Detalhes bibliográficos
Main Authors: Xiaoying Luo, Dan Wang, Xuan Luo, Xintao Zhu, Guozhen Wang, Zuowei Ning, Yang Li, Xiaoxin Ma, Renqiang Yang, Siyi Jin, Yun Huang, Ying Meng, Xu Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017-10-01
Colecção:Redox Biology
Assuntos:
Autophagy
Liver sinusoidal endothelial cell
Defenestration
Aldosterone
Caveolin 1
Oxidation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231717302719
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