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The CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cells
BACKGROUND & AIMS: A fenestrated phenotype is characteristic of liver sinusoidal endothelial cells (LSECs), but liver sinusoids become defenestrated during fibrosis and other liver diseases. Thrombospondin-1 (TSP1) is a matrix glycoprotein with pro-fibrotic effects, and the CD47-binding fragment...
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| Udgivet i: | Liver Int |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4285809/ https://ncbi.nlm.nih.gov/pubmed/23799952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12231 |
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