Nalaganje...
Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice
Cancer cells are poorly immunogenic and have a wide range of mutations, which makes them unsuitable for use in vaccination treatment. Here, we show that elimination of CD47, a ligand for the myeloid cell inhibitory receptor SIRPα, from tumor cells by genetic deletion or antibody blocking, significan...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989506/ https://ncbi.nlm.nih.gov/pubmed/31996683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14102-4 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|