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Structure and allosteric inhibition of excitatory amino acid transporter 1
Human members of the solute carrier 1 (SLC1) family of transporters take up excitatory neurotransmitters in the brain and amino acids in peripheral organs. Dysregulation of their functions is associated to neurodegenerative disorders and cancer. Here we present the first crystal structures of a ther...
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| Pubblicato in: | Nature |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410168/ https://ncbi.nlm.nih.gov/pubmed/28424515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22064 |
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