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Structure and allosteric inhibition of excitatory amino acid transporter 1

Human members of the solute carrier 1 (SLC1) family of transporters take up excitatory neurotransmitters in the brain and amino acids in peripheral organs. Dysregulation of their functions is associated to neurodegenerative disorders and cancer. Here we present the first crystal structures of a ther...

詳細記述

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書誌詳細
出版年:Nature
主要な著者: Canul-Tec, Juan C., Assal, Reda, Cirri, Erica, Legrand, Pierre, Brier, Sébastien, Chamot-Rooke, Julia, Reyes, Nicolas
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410168/
https://ncbi.nlm.nih.gov/pubmed/28424515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22064
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