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Structure and allosteric inhibition of excitatory amino acid transporter 1
Human members of the solute carrier 1 (SLC1) family of transporters take up excitatory neurotransmitters in the brain and amino acids in peripheral organs. Dysregulation of their functions is associated to neurodegenerative disorders and cancer. Here we present the first crystal structures of a ther...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410168/ https://ncbi.nlm.nih.gov/pubmed/28424515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22064 |
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