Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model

Ebola virus (EBOV) is highly pathogenic, with a predisposition to cause outbreaks in human populations accompanied by significant mortality. Owing to the lack of approved therapies, screening programmes of potentially efficacious drugs have been undertaken. One of these studies has demonstrated the...

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Opis bibliograficzny
Wydane w:J Gen Virol
Główni autorzy: Dowall, Stuart D., Bosworth, Andrew, Watson, Robert, Bewley, Kevin, Taylor, Irene, Rayner, Emma, Hunter, Laura, Pearson, Geoff, Easterbrook, Linda, Pitman, James, Hewson, Roger, Carroll, Miles W.
Format: Artigo
Język:Inglês
Wydane: Microbiology Society 2015
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Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410110/
https://ncbi.nlm.nih.gov/pubmed/26459826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000309
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