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Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic

Ebola virus (EBOV) is highly pathogenic, with a predisposition to cause outbreaks in human populations accompanied by significant mortality. An ovine polyclonal antibody therapy has been developed against EBOV, named EBOTAb. When tested in the stringent guinea pig model of EBOV disease, EBOTAb has b...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dowall, Stuart D., Bosworth, Andrew, Rayner, Emma, Taylor, Irene, Landon, John, Cameron, Ian, Coxon, Ruth, Al Abdulla, Ibrahim, Graham, Victoria A., Hall, Graham, Kobinger, Gary, Hewson, Roger, Carroll, Miles W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964638/
https://ncbi.nlm.nih.gov/pubmed/27465308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30497
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