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Development of a Cost-effective Ovine Polyclonal Antibody-Based Product, EBOTAb, to Treat Ebola Virus Infection
The highly glycosylated glycoprotein spike of Ebola virus (EBOV-GP(1,2)) is the primary target of the humoral host response. Recombinant EBOV-GP ectodomain (EBOV-GP(1,2ecto)) expressed in mammalian cells was used to immunize sheep and elicited a robust immune response and produced high titers of hig...
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Publicado no: | J Infect Dis |
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Main Authors: | , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779302/ https://ncbi.nlm.nih.gov/pubmed/26715676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv565 |
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