Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model

Ebola virus (EBOV) is highly pathogenic, with a predisposition to cause outbreaks in human populations accompanied by significant mortality. Owing to the lack of approved therapies, screening programmes of potentially efficacious drugs have been undertaken. One of these studies has demonstrated the...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Dowall, Stuart D., Bosworth, Andrew, Watson, Robert, Bewley, Kevin, Taylor, Irene, Rayner, Emma, Hunter, Laura, Pearson, Geoff, Easterbrook, Linda, Pitman, James, Hewson, Roger, Carroll, Miles W.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2015
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410110/
https://ncbi.nlm.nih.gov/pubmed/26459826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000309
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