Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

BACKGROUND: Artemisinin-based combination therapies are the first line of treatment for Plasmodium falciparum infections worldwide, but artemisinin resistance has risen rapidly in Southeast Asia over the past decade. Mutations in the kelch13 gene have been implicated in this resistance. We used long...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Cerqueira, Gustavo C., Cheeseman, Ian H., Schaffner, Steve F., Nair, Shalini, McDew-White, Marina, Phyo, Aung Pyae, Ashley, Elizabeth A., Melnikov, Alexandre, Rogov, Peter, Birren, Bruce W., Nosten, François, Anderson, Timothy J. C., Neafsey, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410087/
https://ncbi.nlm.nih.gov/pubmed/28454557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1204-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados