Regulatory T cells promote myelin regeneration in the Central Nervous System

Regeneration of central nervous system (CNS) myelin involves differentiation of oligodendrocytes from oligodendrocyte progenitor cells (OPC). In multiple sclerosis (MS), remyelination can fail despite abundant OPC, suggesting impairment of oligodendrocyte differentiation. T cells infiltrate the CNS...

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Bibliografiska uppgifter
I publikationen:Nat Neurosci
Huvudupphovsmän: Dombrowski, Yvonne, O’Hagan, Thomas, Dittmer, Marie, Penalva, Rosana, Mayoral, Sonia R., Bankhead, Peter, Fleville, Samara, Eleftheriadis, George, Zhao, Chao, Naughton, Michelle, Hassan, Rachel, Moffat, Jill, Falconer, John, Boyd, Amanda, Hamilton, Peter, Allen, Ingrid V., Kissenpfennig, Adrien, Moynagh, Paul N., Evergren, Emma, Perbal, Bernard, Williams, Anna C., Ingram, Rebecca J., Chan, Jonah R., Franklin, Robin J.M., Fitzgerald, Denise C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409501/
https://ncbi.nlm.nih.gov/pubmed/28288125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4528
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